How It Works

Cattle experience stress from everyday events — weaning, transportation, vaccination, and weather changes. These stressors activate the brain’s threat response, increasing cortisol and inflammation while lowering immunity and feed efficiency.

CattleZen™ helps cattle stay calm by addressing the brain’s perception of threat — not just the symptoms of stress.

Why is reducing stress important for cattle?

Stress triggers the release of cortisol and adrenaline, which can suppress the immune system, reduce feed intake, and slow weight gain. By reducing the perception of threat, CattleZen helps cattle stay calm, eat better, and perform more efficiently.

Dual-Pheromone Calming Technology

CattleZen is a patented product that combines two pheromones to help reduce stress, enhance performance, and support animal welfare for healthier, more profitable cattle.

Pheromone 1: Maternal Bovine Appeasing Substance (MBAS) Analogue

Modeled after a naturally occurring substance secreted by the skin of lactating cows, MBAS helps reduce stress and promote a sense of calmness in cattle. It provides a sustained, long-lasting calming effect.

Pheromone 2: 2M2B Calming Pheromone

A complementary pheromone delivers a fast-acting calming response, helping animals settle quickly.

Together, these two pheromones create an ideal balance of fast-action and sustained calming. When applied to the skin above the muzzle, CattleZen’s pheromones are detected by the vomeronasal organ inside the nasal cavity — a key sensory organ that interprets chemical communication.

The result? Calming signals reach the brain regions that regulate fear and stress, helping cattle feel safe, relaxed, and easier to handle — even in challenging situations.

Step-by-Step: How it Works

1. Apply above the muzzle

A quick, single-site, topical application to the skin above the muzzle. No injection, no ingestion — just apply and go.

2. Pheromones are detected

The animal inhales the pheromone blend, which is sensed by the vomeronasal organ.

3. Calming signals are sent to the brain

These signals desensitize the amygdala and hypothalamus, the parts of the brain that control stress and fear.

4. Stress response decreases

The animal’s perception of threat is reduced, helping lower cortisol and minimize the impact of stressful events.

5. Observable results

Cattle show less agitation, better feed intake, improved immunity, and enhanced daily gain.

The benefits of calmer cattle

CattleZen’s natural calming effect supports:

  • Enhanced cattle welfare and safety
  • Improved handler safety
  • Lower cortisol and inflammation
  • Improved vaccine response and immunity
  • Increased average daily gain
  • Decreased morbidity and mortality

To learn more or connect with a representative, visit our contact page.